Diarrhea and nausea can occur when too much creatine is taken at once, in which case doses should be spread out throughout the day and taken with meals. You may experience a decrease in appetite, stomach pain, diarrhea, nausea and vomiting. Mayo Clinic is a nonprofit organization and proceeds from Web advertising help support our mission. All rights reserved. http://www.micromedexsolutions.com. Creatine supplements are found in many forms but we’ll be measuring the 2 most popular versions, Monohydrate and Hydrochloride (HCL). Although perfectly safe, some users may suffer certain side effects from taking creatine, such as cramps, weight gain, kidney stones, and digestive problems. Micromedex 2.0 Healthcare Series. Creatine, one of the most widely used natural supplements in almost every major competitive sport. When taken without sufficient water, stomach cramping can occur. The most reported side effects from creatine supplementation include headaches, dehydration, gastric disturbances, and possibly muscle cramps. Heat intolerance 10. Tell your Creatine Side Effects & Risks Creatine supplementation should be safe when used by healthy individuals. Due to the bad reputation of performance … Question: What are the possible side effects of creatine monohydrate supplements? Using different formulations together increases the risk of an overdose. However, there is concern that creatine taken in high doses is possibly unsafe and could damage the liver, kidneys or heart.Creatine can cause: 1. When you should not make use of creatine supplements. But given that the substance affects individuals differently, you should be aware of some side effects that may offer, … People also use oral creatine to treat certain brain disorders, congestive heart failure and other conditions. Creatine (sometimes referred to as creatine monohydrate) has been called a “phenomenon” in the bodybuilding community and is among the best-selling supplements to gain muscle. Call your doctor for medical Learn More . We comply with the HONcode standard for trustworthy health information -. Check out these best-sellers and special offers on books and newsletters from Mayo Clinic. Depending on who you ask, the suggested side effects of creatine may include: Kidney damage Liver damage Kidney stones Weight gain Bloating Dehydration Muscle cramps Digestive problems Compartment syndrome Rhabdomyolysis Topical creatine might be used to treat aging skin. There also is some concern that creatine might increase mania in people who have bipolar disorder. As we’ve mentioned in the side effects section, creatine might cause water retention. Accessed July 26, 2017. The prostate gland produces most of the constituents of semen, but not the sperm cells. Creatine. Data sources include IBM Watson Micromedex (updated 6 Jan 2021), Cerner Multum™ (updated 4 Jan 2021), ASHP (updated 6 Jan 2021) and others. Our general interest e-newsletter keeps you up to date on a wide variety of health topics. There have been anecdotal reports of kidney damage, blood sugar concerns, heart problems, muscle cramps and pulls, dehydration, and diarrhea, in addition to … Last updated on May 23, 2020. When you should not make use of creatine supplements. Download FREE Practo app. Some people, especially athletes, need extra amounts of creatine in order to improve physical performance. Is creatine safe? However, like most nutritional supplements, creatine supplements are not strictly regulated and thus can produce numerous, possibly dangerous, side effects. Common creatine side effects may include: nausea, stomach pain; diarrhea; muscle cramps; or weight gain. Myth 3: Creatine Causes Cramping and Dehydration. If you have questions about side effects, call your doctor. Creatine supplementation should be safe when used by healthy individuals. That might cause some temporary weight gain due to the fluids building up. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. But like any supplement, there is a chance that it can cause unwanted side effects. People who are using creatine believes that it enhances their performance in the gym, increase their endurance, increase in their muscle mass also recover muscles more efficiently during working out. Creatine benefits are the most pronounced when the athlete is well-hydrated and has sufficient magnesium intake. The body's liver, pancreas and kidneys also make creatine. When combined with other supplements or taken at higher than recommended doses for several months, there have been cases of liver and renal complications with creatine. The thing is, these side effects are caused by not using creatine properly and can easily be avoided. When people talk about side effects from a drug or supplement, they are generally referring to a potentially debilitating effect. However, creatine users have reported cramping, diarrhea, dehydration, and asthma after initiating use of the drug. What are the possible side effects of creatine monohydrate supplements? This content does not have an English version. It’s located in the middle of the pelvis, close to the lower part of the bladder where the urethra exits. Most cases that report negative side effects are a result of misusing the dosage or failing to take the supplement with enough water. Offering major health benefits for a cheap average price point. Water retention 9. Like any supplement, you’re always advised to seek medical advice before taking it. Your body converts creatine to phosphocreatine and stores it in your muscles, where it's used for energy. Mostly they occur in the loading phase due to the particularly high dosage. Even though creatine is said to have many undesirable effects, the probability of proven side effects is relatively low. Even so, a capability between high doses and these harmful side effects has not been found. Creatine dosage is dependant on the condition for which it is being used and varies between different ages, sex, and medical conditions. Accessed July 26, 2017. Suppression of the Body’s Ability to Synthesize Creatine – The fear here is that the body will lose its … Creatine might benefit athletes who need short bursts of speed or muscle, such as sprinters and weight lifters. While taking creatine might not help all athletes, evidence suggests it generally won't hurt if taken as directed. What is creatine, what does it do, what are the benefits, how and when should it be taken, does it really work, how safe is it, are there any side effects, what brand and … Gastrointestinal disturbances and muscle cramps have been reported occasionally in healthy individuals, but the effects are anecdotal. Most of the health risks attributed to creatine (kidney and liver damage, increased risk of injury) have not been shown in clinical studies. Dizziness 5. No doubt, creatine ester side effects are reported to be much lesser than that of creatine monohydrate. Is creatine safe? They're more likely to occur in people who take creatine supplements for six months or longer. Accessed July 27, 2017. However, you should keep in mind that: If you take creatine supplements, you may gain weight because of water retention in your body’s muscles. http://www.wolterskluwercdi.com/facts-comparisons-online/. A single copy of these materials may be reprinted for noncommercial personal use only. 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